He works too hard.That is ____is wrong with him.A.that,whichB.that whatC.the thing whatD.whatis wrong with

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He works too hard.That is ____is wrong with him.A.that,whichB.that whatC.the thing whatD.whatis wrong with
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He works too hard.That is ____is wrong with him.A.that,whichB.that whatC.the thing whatD.whatis wrong with
He works too hard.That is ____is wrong with him.
A.that,which
B.that what
C.the thing what
D.what
is wrong with

He works too hard.That is ____is wrong with him.A.that,whichB.that whatC.the thing whatD.whatis wrong with
D
That is 代指He works too hard这件事
____is wrong with him 中what作主语
如果用一般陈述句就是
What is wrong with him

D.
意思是:他工作太努力了.那是他个人的问题.

我选D,what 在这里作 that is 的宾语,同时又作后一句的主语!
个人意见,仅供参考哈!
be wrong with 在这里是问题所在的意思吧!

指对某人有困难吧,我猜的。